Varaico: Literature-Extracted Genetic Variants

VCAM1

391 papers

RefSeq Summary

This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell a...

Pfam Domains

I-setaa 25–112UCSCImmunoglobulin I-set domain

C2-setaa 133–221UCSCImmunoglobulin C2-set domain

igaa 232–304UCSCImmunoglobulin domain

I-setaa 313–400UCSCImmunoglobulin I-set domain

C2-setaa 421–509UCSCImmunoglobulin C2-set domain

Ig_3aa 514–583UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

vascular cell adhesion molecule 1

HGNC Alias Symbol

CD106

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001078.4

p.C335S

c.1004G>C

Surrounding Variants

1 paper

NM_001078.4

p.D329Y

c.985G>T

1 paper

NM_001078.4

p.Q350H

c.1050G>T

3 papers

NM_001078.4

p.S318F

c.953C>T

1 paper

NM_001078.4

p.I317insFs

c.949_950insA

1 paper

NM_001078.4

p.S356R

c.1068C>A

1 paper

NM_001078.4

p.S361N

c.1082G>A

1 paper

NM_001078.4

p.E362K

c.1084G>A

1 paper

NM_001078.4

p.G363R

c.1087G>A

1 paper

NM_001078.4

p.P372insFs

c.1115dupC

2 papers

NM_001078.4

p.P372L

c.1115C>T

1 paper

NM_001078.4

p.P372delFs

c.1116delT

1 paper

NM_001078.4

p.E376_N377delFs

c.1127_1131del5