Varaico: Literature-Extracted Genetic Variants

VEGFA

2,180 papers

RefSeq Summary

This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration ...

Pfam Domains

VEGFAaa 1–22UCSCVascular endothelial growth factor A, long form-like domain

PDGFaa 24–102UCSCPDGF/VEGF domain

VEGF_Caa 110–163UCSCVEGF heparin-binding domain

Gene Aliases

HGNC Name

vascular endothelial growth factor A

HGNC Previous Symbol

VEGF

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

9 papers

NM_003376.6

p.Q137*

c.409C>T

Surrounding Variants

1 paper

NM_003376.6

p.Q137R

c.410A>G

1 paper

NM_003376.6

p.P136_Q137insFs

c.408_409insT

1 paper

NM_003376.6

p.P136_Q137Fs

c.407_409delinsGFs

1 paper

NM_003376.6

p.P136A

c.406C>G

6 papers

NM_003376.6

p.P136S

c.406C>T

1 paper

NM_003376.6

p.A138fs

c.412_413fs

1 paper

NM_003376.6

p.A138_A140delFs

c.413_419del7

1 paper

NM_003376.6

p.A138V

c.413C>T

2 papers

NM_003376.6

p.A135A

c.405T>C

2 papers

NM_003376.6

p.A135G

c.404C>G

1 paper

NM_003376.6

p.A135V

c.404C>T

1 paper

NM_003376.6

p.L139V

c.415C>G