Varaico: Literature-Extracted Genetic Variants

VEGFA

2,180 papers

RefSeq Summary

This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration ...

Pfam Domains

VEGFAaa 1–22UCSCVascular endothelial growth factor A, long form-like domain

PDGFaa 24–102UCSCPDGF/VEGF domain

VEGF_Caa 110–163UCSCVEGF heparin-binding domain

Gene Aliases

HGNC Name

vascular endothelial growth factor A

HGNC Previous Symbol

VEGF

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003376.6

p.L139V

c.415C>G

Surrounding Variants

1 paper

NM_003376.6

p.L139_R141delins

c.415_421delinsAACCCTA

6 papers

NM_003376.6

p.L139P

c.416T>C

1 paper

NM_003376.6

p.A138V

c.413C>T

1 paper

NM_003376.6

p.A140T

c.418G>A

3 papers

NM_003376.6

p.A140P

c.418G>C

1 paper

NM_003376.6

p.A138fs

c.412_413fs

1 paper

NM_003376.6

p.A138_A140delFs

c.413_419del7

1 paper

NM_003376.6

p.A140G

c.419C>G

1 paper

NM_003376.6

p.Q137R

c.410A>G

1 paper

NM_003376.6

p.A140A

c.420C>G

2 papers

NM_003376.6

p.R141R

c.421C>A

9 papers

NM_003376.6

p.Q137*

c.409C>T