vascular endothelial growth factor D

FIGF

VEGF-D

c-fos induced growth factor (vascular endothelial growth factor D)

Vascular endothelial growth factor D

c-Fos-induced growth factor

The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus. [provided by RefSeq, Feb 2011].

Varaico: Literature-Extracted Genetic Variants

VEGFD

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol