Varaico: Literature-Extracted Genetic Variants

WARS1

71 papers

RefSeq Summary

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-...

Pfam Domains

WHEP-TRSaa 12–64UCSCWHEP-TRS domain

tRNA-synt_1baa 151–443UCSCtRNA synthetases class I (W and Y)

Gene Aliases

HGNC Name

tryptophanyl-tRNA synthetase 1

HGNC Previous Symbol

IFI53

Papers

RefSeq ID

Protein change

DNA change

1–12 of 66 variants

14 papers

NM_004184.4

p.H257R

c.770A>G

5 papers

NM_004184.4

p.D314G

c.941A>G

4 papers

NM_004184.4

p.F138Y

c.413T>A

3 papers

NM_004184.4

p.A333T

c.997G>A

3 papers

NM_004184.4

p.N356I

c.1067A>T

3 papers

NM_004184.4

p.R448W

c.1342C>T

2 papers

NM_004184.4

p.R133C

c.397C>T

2 papers

NM_004184.4

p.G163V

c.488G>T

2 papers

NM_004184.4

p.V251M

c.751G>A

2 papers

NM_004184.4

p.D419N

c.1255G>A

1 paper

NM_004184.4

p.M1V

c.1A>G

1 paper

NM_004184.4

p.E5insFs

c.14dupA