Varaico: Literature-Extracted Genetic Variants

WARS1

71 papers

RefSeq Summary

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-...

Pfam Domains

WHEP-TRSaa 12–64UCSCWHEP-TRS domain

tRNA-synt_1baa 151–443UCSCtRNA synthetases class I (W and Y)

Gene Aliases

HGNC Name

tryptophanyl-tRNA synthetase 1

HGNC Previous Symbol

IFI53

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004184.4

p.T383A

c.1147A>G

Surrounding Variants

1 paper

NM_004184.4

p.E385K

c.1153G>A

1 paper

NM_004184.4

p.E408K

c.1222G>A

1 paper

NM_004184.4

p.D409N

c.1225G>A

1 paper

NM_004184.4

p.D410D

c.1230C>T

2 papers

NM_004184.4

p.D419N

c.1255G>A

1 paper

NM_004184.4

p.K431R

c.1292A>G

1 paper

NM_004184.4

p.A443S

c.1327G>T

3 papers

NM_004184.4

p.R448W

c.1342C>T

3 papers

NM_004184.4

p.N356I

c.1067A>T

1 paper

NM_004184.4

p.A346T

c.1036G>A

3 papers

NM_004184.4

p.A333T

c.997G>A

1 paper

NM_004184.4

p.R326S

c.978G>C