Varaico: Literature-Extracted Genetic Variants

WARS1

71 papers

RefSeq Summary

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-...

Pfam Domains

WHEP-TRSaa 12–64UCSCWHEP-TRS domain

tRNA-synt_1baa 151–443UCSCtRNA synthetases class I (W and Y)

Gene Aliases

HGNC Name

tryptophanyl-tRNA synthetase 1

HGNC Previous Symbol

IFI53

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

14 papers

NM_004184.4

p.H257R

c.770A>G

Surrounding Variants

1 paper

NM_004184.4

p.H257Q

c.771T>G

1 paper

NM_004184.4

p.H257Q

c.771T>A

2 papers

NM_004184.4

p.V251M

c.751G>A

1 paper

NM_004184.4

p.R300delFs

c.898_899delCT

5 papers

NM_004184.4

p.D314G

c.941A>G

1 paper

NM_004184.4

p.A324T

c.970G>A

1 paper

NM_004184.4

p.R326S

c.978G>C

3 papers

NM_004184.4

p.A333T

c.997G>A

1 paper

NM_004184.4

p.A346T

c.1036G>A

3 papers

NM_004184.4

p.N356I

c.1067A>T

1 paper

NM_213645.2

p.A174A

c.522T>C

1 paper

NM_004184.4

p.Y214D

c.640T>G