Varaico: Literature-Extracted Genetic Variants

WARS1

71 papers

RefSeq Summary

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-...

Pfam Domains

WHEP-TRSaa 12–64UCSCWHEP-TRS domain

tRNA-synt_1baa 151–443UCSCtRNA synthetases class I (W and Y)

Gene Aliases

HGNC Name

tryptophanyl-tRNA synthetase 1

HGNC Previous Symbol

IFI53

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004184.4

p.I136I

c.408C>T

Surrounding Variants

4 papers

NM_004184.4

p.F138Y

c.413T>A

2 papers

NM_004184.4

p.R133C

c.397C>T

1 paper

NM_004184.4

p.R127K

c.380G>A

1 paper

NM_004184.4

p.R119*

c.355C>T

1 paper

NM_004184.4

p.I112T

c.335T>C

1 paper

NM_004184.4

p.K111N

c.333A>T

1 paper

NM_004184.4

p.S109fs

c.325_326fs

1 paper

NM_004184.4

p.R106L

c.317G>T

1 paper

NM_004184.4

p.R106Q

c.317G>A

1 paper

NM_004184.4

p.I104L

c.310A>C

1 paper

NM_004184.4

p.K102M

c.305A>T

1 paper

NM_004184.4

p.K102R

c.305A>G