Varaico: Literature-Extracted Genetic Variants

Gene:WEE1
Variant:p.E70D

WEE1

147 papers

RefSeq Summary

This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kina...

Pfam Domains

Pkinaseaa 299–569UCSCProtein kinase domain

Gene Aliases

HGNC Name

WEE1 G2 checkpoint kinase

HGNC Alias Symbol

WEE1A

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
5 papers
NM_003390.4
p.E70D
c.210G>C
Surrounding Variants
1 paper
NM_003390.4
p.E70K
c.208G>A
1 paper
NM_003390.4
p.S67R
c.201C>A
1 paper
NM_003390.4
p.S67R
c.201C>G
1 paper
NM_003390.4
p.S67R
c.199A>C
1 paper
NM_003390.4
p.R75S
c.223C>A
1 paper
NM_003390.4
p.R76delFs
c.227_228delGC
1 paper
NM_003390.4
p.R76S
c.226C>A
1 paper
NM_003390.4
p.P79H
c.236C>A
1 paper
NM_003390.4
p.P81S
c.241C>T
1 paper
NM_003390.4
p.P81L
c.242C>T
1 paper
NM_003390.4
p.P83delFs
c.249delC
1 paper
NM_003390.4
p.G84fs
c.250_251fs
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