Varaico: Literature-Extracted Genetic Variants

Gene:WEE1
Variant:p.D148N

WEE1

147 papers

RefSeq Summary

This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kina...

Pfam Domains

Pkinaseaa 299–569UCSCProtein kinase domain

Gene Aliases

HGNC Name

WEE1 G2 checkpoint kinase

HGNC Alias Symbol

WEE1A

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_003390.4
p.D148N
c.442G>A
Surrounding Variants
1 paper
NM_003390.4
p.D148_A149del2
c.442_446del6
1 paper
NM_003390.4
p.P146S
c.436C>T
1 paper
NM_003390.4
p.R152Q
c.455G>A
1 paper
NM_003390.4
p.R142S
c.424C>A
1 paper
NM_003390.4
p.R158L
c.473G>T
1 paper
NM_003390.4
p.A159V
c.476C>T
1 paper
NM_003390.4
p.G162A
c.485G>C
1 paper
NM_003390.4
p.Y132*
c.396C>A
1 paper
NM_003390.4
p.Y132*
c.396C>G
1 paper
NM_003390.4
p.Y132H
c.394T>C
1 paper
NM_003390.4
p.P168Q
c.503C>A
2 papers
NM_003390.4
p.P128_A130del3
c.382_389del9
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."