WAP four-disulfide core domain 12

C20orf122

dJ211D12.4

WAP2

chromosome 20 open reading frame 122

WAP four-disulfide core domain protein 12

Putative protease inhibitor WAP12

Whey acidic protein 2

WAP-type (Whey Acidic Protein) 'four-disulfide core'

This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. [provided by RefSeq, Jul 2008].

Varaico: Literature-Extracted Genetic Variants

WFDC12

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol