WAP four-disulfide core domain 6

C20orf171

dJ461P17.11

WAP6

chromosome 20 open reading frame 171

WAP four-disulfide core domain protein 6

Putative protease inhibitor WAP6

This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Read-through transcription exists between this gene and the upstream SPINLW1 (serine peptidase inhibitor-like, with Kunitz and WAP domains 1) gene. [provided by RefSeq, Nov 2010].

Varaico: Literature-Extracted Genetic Variants

WFDC6

RefSeq Summary

Gene Aliases

HGNC Name

HGNC Previous Symbol