Varaico: Literature-Extracted Genetic Variants

WNK1

951 papers

RefSeq Summary

This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride io...

Pfam Domains

Pkinaseaa 221–479UCSCProtein kinase domain

OSR1_Caa 500–563UCSCOxidative-stress-responsive kinase 1 C-terminal domain

CCTL2_WNKaa 870–947UCSCWNK CCTL2 domain

CCTL2_WNKaa 1117–1194UCSCWNK CCTL2 domain

Gene Aliases

HGNC Name

WNK lysine deficient protein kinase 1

HGNC Previous Symbols

PRKWNK1; HSN2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_018979.4

p.S2T

c.4T>A

Surrounding Variants

1 paper

NM_018979.4

p.S2ins0

c.4_6dupTCT

1 paper

NM_018979.4

p.M1T

c.2T>C

1 paper

NM_018979.4

p.S2S

c.6T>G

1 paper

NM_018979.4

p.M1insFs

c.2dupT

1 paper

NM_018979.4

p.M1L

c.1A>C

1 paper

NM_018979.4

p.M1L

c.1A>T

2 papers

NM_018979.4

p.G3insFs

c.7_8insT

2 papers

NM_018979.4

p.G3insFs

c.7_8insTT

1 paper

NM_018979.4

p.G4C

c.10G>T

1 paper

NM_018979.4

p.A5T

c.13G>A

1 paper

NM_018979.4

p.A5A

c.15C>A

1 paper

NM_018979.4

p.A6delFs

c.17delC