Varaico: Literature-Extracted Genetic Variants

WNK1

951 papers

RefSeq Summary

This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride io...

Pfam Domains

Pkinaseaa 221–479UCSCProtein kinase domain

OSR1_Caa 500–563UCSCOxidative-stress-responsive kinase 1 C-terminal domain

CCTL2_WNKaa 870–947UCSCWNK CCTL2 domain

CCTL2_WNKaa 1117–1194UCSCWNK CCTL2 domain

Gene Aliases

HGNC Name

WNK lysine deficient protein kinase 1

HGNC Previous Symbols

PRKWNK1; HSN2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_018979.4

p.A92T

c.274G>A

Surrounding Variants

1 paper

NM_018979.4

p.T91P

c.271A>C

1 paper

NM_018979.4

p.L95insFs

c.283dupC

1 paper

NM_018979.4

p.S88T

c.262T>A

2 papers

NM_018979.4

p.P96P

c.288C>T

2 papers

NM_018979.4

p.C86C

c.258T>C

2 papers

NM_018979.4

p.L98F

c.292C>T

1 paper

NM_018979.4

p.I85N

c.254T>A

1 paper

NM_018979.4

p.I85delFs

c.255delC

1 paper

NM_018979.4

p.V84delFs

c.252delC

1 paper

NM_018979.4

p.S101T

c.301T>A

1 paper

NM_018979.4

p.S101P

c.301T>C

1 paper

NM_018979.4

p.S101A

c.301T>G