Varaico: Literature-Extracted Genetic Variants

WNK1

951 papers

RefSeq Summary

This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride io...

Pfam Domains

Pkinaseaa 221–479UCSCProtein kinase domain

OSR1_Caa 500–563UCSCOxidative-stress-responsive kinase 1 C-terminal domain

CCTL2_WNKaa 870–947UCSCWNK CCTL2 domain

CCTL2_WNKaa 1117–1194UCSCWNK CCTL2 domain

Gene Aliases

HGNC Name

WNK lysine deficient protein kinase 1

HGNC Previous Symbols

PRKWNK1; HSN2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_018979.4

p.S158C

c.472A>T

Surrounding Variants

1 paper

NM_018979.4

p.P157P

c.471C>T

1 paper

NM_018979.4

p.P157H

c.470C>A

1 paper

NM_018979.4

p.P157delins

c.470_471delinsTG

1 paper

NM_018979.4

p.T155S

c.463A>T

1 paper

NM_018979.4

p.S154P

c.460T>C

1 paper

NM_018979.4

p.P153P

c.459C>T

1 paper

NM_018979.4

p.D163V

c.488A>T

1 paper

NM_018979.4

p.G150G

c.450C>T

4 papers

NM_018979.4

p.A149V

c.446C>T

1 paper

NM_018979.4

p.Q168*

c.502C>T

1 paper

NM_018979.4

p.P169S

c.505C>T

1 paper

NM_018979.4

p.L171F

c.511C>T