Varaico: Literature-Extracted Genetic Variants

WNK1

951 papers

RefSeq Summary

This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride io...

Pfam Domains

Pkinaseaa 221–479UCSCProtein kinase domain

OSR1_Caa 500–563UCSCOxidative-stress-responsive kinase 1 C-terminal domain

CCTL2_WNKaa 870–947UCSCWNK CCTL2 domain

CCTL2_WNKaa 1117–1194UCSCWNK CCTL2 domain

Gene Aliases

HGNC Name

WNK lysine deficient protein kinase 1

HGNC Previous Symbols

PRKWNK1; HSN2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_018979.4

p.A1384V

c.4151C>T

Surrounding Variants

1 paper

NM_018979.4

p.E1381*

c.4141G>T

1 paper

NM_018979.4

p.S1373fs

c.4117_4118fs

1 paper

NM_018979.4

p.S1406P

c.4216T>C

1 paper

NM_018979.4

p.S1423S

c.4269A>G

1 paper

NM_018979.4

p.I1424M

c.4272A>G

1 paper

NM_018979.4

p.S1428F

c.4283C>T

1 paper

NM_213655.5

p.F1591_L1592del2

c.4771_4775del6

1 paper

NM_018979.4

p.Q1432R

c.4295A>G

1 paper

NM_018979.4

p.P1334L

c.4001C>T

1 paper

NM_001184985.2

p.P1591_T1592del2

c.4771_4775del6

1 paper

NM_018979.4

p.I1440I

c.4320C>T

1 paper

NM_018979.4

p.T1452A

c.4354A>G