Varaico: Literature-Extracted Genetic Variants

WNK1

951 papers

RefSeq Summary

This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride io...

Pfam Domains

Pkinaseaa 221–479UCSCProtein kinase domain

OSR1_Caa 500–563UCSCOxidative-stress-responsive kinase 1 C-terminal domain

CCTL2_WNKaa 870–947UCSCWNK CCTL2 domain

CCTL2_WNKaa 1117–1194UCSCWNK CCTL2 domain

Gene Aliases

HGNC Name

WNK lysine deficient protein kinase 1

HGNC Previous Symbols

PRKWNK1; HSN2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_018979.4

p.G1732G

c.5196G>A

Surrounding Variants

1 paper

NM_018979.4

p.S1743P

c.5227T>C

1 paper

NM_018979.4

p.N1715S

c.5144A>G

1 paper

NM_018979.4

p.K1753R

c.5258A>G

1 paper

NM_018979.4

p.T1704A

c.5110A>G

1 paper

NM_018979.4

p.S1700R

c.5098A>C

1 paper

NM_213655.5

p.I1944_L1955delFs

c.5832_5865del34

1 paper

NM_018979.4

p.S1681P

c.5041T>C

1 paper

NM_018979.4

p.A1646G

c.4937C>G

1 paper

NM_018979.4

p.P1644L

c.4931C>T

1 paper

NM_018979.4

p.T1616A

c.4846A>G

1 paper

NM_018979.4

p.T1591_P1592del2

c.4771_4775del6

2 papers

NM_018979.4

p.A1546_P1547insC

c.4636_4640ins3