Varaico: Literature-Extracted Genetic Variants

WNK1

951 papers

RefSeq Summary

This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride io...

Pfam Domains

Pkinaseaa 221–479UCSCProtein kinase domain

OSR1_Caa 500–563UCSCOxidative-stress-responsive kinase 1 C-terminal domain

CCTL2_WNKaa 870–947UCSCWNK CCTL2 domain

CCTL2_WNKaa 1117–1194UCSCWNK CCTL2 domain

Gene Aliases

HGNC Name

WNK lysine deficient protein kinase 1

HGNC Previous Symbols

PRKWNK1; HSN2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_018979.4

p.M1808I

c.5424G>C

NM_014823.3

p.M1561I

c.4683G>C

Surrounding Variants

6 papers

NM_018979.4

p.M1808I

c.5424G>A

NM_014823.3

p.M1561I

c.4683G>A

6 papers

NM_018979.4

p.M1808I

c.5424G>T

NM_014823.3

p.M1561I

c.4683G>T

1 paper

NM_018979.4

p.A1814V

c.5441C>T

2 papers

NM_018979.4

p.Q1799E

c.5395C>G

1 paper

NM_018979.4

p.E1794D

c.5382G>C

1 paper

NM_018979.4

p.P1817L

c.5450C>T

1 paper

NM_018979.4

p.P1823L

c.5468C>T

1 paper

NM_001184985.2

p.L2038R

c.6113T>G

1 paper

NM_018979.4

p.G1765S

c.5293G>A

1 paper

NM_018979.4

p.K1753R

c.5258A>G

1 paper

NM_018979.4

p.S1743P

c.5227T>C

1 paper

NM_018979.4

p.G1732G

c.5196G>A