Varaico: Literature-Extracted Genetic Variants

WNK1

951 papers

RefSeq Summary

This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride io...

Pfam Domains

Pkinaseaa 221–479UCSCProtein kinase domain

OSR1_Caa 500–563UCSCOxidative-stress-responsive kinase 1 C-terminal domain

CCTL2_WNKaa 870–947UCSCWNK CCTL2 domain

CCTL2_WNKaa 1117–1194UCSCWNK CCTL2 domain

Gene Aliases

HGNC Name

WNK lysine deficient protein kinase 1

HGNC Previous Symbols

PRKWNK1; HSN2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014823.3

p.S1602del1

c.4804_4805delTCA

Surrounding Variants

1 paper

NM_018979.4

p.T1848_S1850del0

c.5542_5550del9

1 paper

NM_001184985.2

p.P2104A

c.6310C>G

1 paper

NM_018979.4

p.E1842ins1

c.5524_5525insGAA

1 paper

NM_018979.4

p.D1867D

c.5601C>T

1 paper

NM_018979.4

p.D1879N

c.5635G>A

1 paper

NM_018979.4

p.A1880T

c.5638G>A

1 paper

NM_018979.4

p.S1918F

c.5753C>T

1 paper

NM_018979.4

p.S1931*

c.5792C>A

1 paper

NM_018979.4

p.S1931*

c.5792C>G

1 paper

NM_018979.4

p.G1944_V1955delFs

c.5832_5865del34

5 papers

NM_018979.4

p.R1945C

c.5833C>T

NM_001184985.2

p.R2205C

c.6613C>T

1 paper

NM_018979.4

p.T1950I

c.5849C>T