Varaico: Literature-Extracted Genetic Variants

WNK1

951 papers

RefSeq Summary

This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride io...

Pfam Domains

Pkinaseaa 221–479UCSCProtein kinase domain

OSR1_Caa 500–563UCSCOxidative-stress-responsive kinase 1 C-terminal domain

CCTL2_WNKaa 870–947UCSCWNK CCTL2 domain

CCTL2_WNKaa 1117–1194UCSCWNK CCTL2 domain

Gene Aliases

HGNC Name

WNK lysine deficient protein kinase 1

HGNC Previous Symbols

PRKWNK1; HSN2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_018979.4

p.S2011Y

c.6032C>A

Surrounding Variants

1 paper

NM_001184985.2

p.P2254L

c.6761C>T

1 paper

NM_018979.4

p.N2045T

c.6134A>C

1 paper

NM_018979.4

p.S2047N

c.6140G>A

1 paper

NM_213655.5

p.T2220_D2221insC

c.6658_6662ins3

1 paper

NM_018979.4

p.K1966E

c.5896A>G

2 papers

NM_018979.4

p.R1957C

c.5869C>T

1 paper

NM_018979.4

p.D2069N

c.6205G>A

1 paper

NM_018979.4

p.N1953_K1954insA

c.5857_5861ins3

1 paper

NM_018979.4

p.T1951A

c.5851A>G

1 paper

NM_018979.4

p.T1950I

c.5849C>T

5 papers

NM_018979.4

p.R1945C

c.5833C>T

NM_001184985.2

p.R2205C

c.6613C>T

1 paper

NM_018979.4

p.G1944_V1955delFs

c.5832_5865del34