Varaico: Literature-Extracted Genetic Variants

WNK2

176 papers

RefSeq Summary

The protein encoded by this gene is a cytoplasmic serine-threonine kinase that belongs to the protein kinase superfamily. The protein plays an important role in the regulation of electrolyte homeostas...

Pfam Domains

Pkinaseaa 195–453UCSCProtein kinase domain

OSR1_Caa 474–537UCSCOxidative-stress-responsive kinase 1 C-terminal domain

CCTL2_WNKaa 1186–1263UCSCWNK CCTL2 domain

Gene Aliases

HGNC Name

WNK lysine deficient protein kinase 2

HGNC Previous Symbols

SDCCAG43; PRKWNK2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006648.4

p.S1877L

c.5630C>T

Surrounding Variants

1 paper

NM_006648.4

p.S1877S

c.5631G>A

1 paper

NM_006648.4

p.T1867M

c.5600C>T

1 paper

NM_006648.4

p.M1863T

c.5588T>C

1 paper

NM_006648.4

p.R1849W

c.5545C>T

1 paper

NM_006648.4

p.K1838T

c.5513A>C

1 paper

NM_006648.4

p.D1835N

c.5503G>A

1 paper

NM_006648.4

p.L1826L

c.5476C>T

1 paper

NM_006648.4

p.Q1821R

c.5462A>G

3 papers

NM_006648.4

p.V1801G

c.5402T>G

1 paper

NM_006648.4

p.T1793M

c.5378C>T

1 paper

NM_006648.4

p.L1786R

c.5357T>G

1 paper

NM_006648.4

p.D1772N

c.5314G>A