Varaico: Literature-Extracted Genetic Variants

WNK3

144 papers

RefSeq Summary

This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved l...

Pfam Domains

Pkinaseaa 147–405UCSCProtein kinase domain

OSR1_Caa 426–489UCSCOxidative-stress-responsive kinase 1 C-terminal domain

CCTL2_WNKaa 743–819UCSCWNK CCTL2 domain

Gene Aliases

HGNC Name

WNK lysine deficient protein kinase 3

HGNC Previous Symbol

PRKWNK3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_020922.5

p.D1607E

c.4821C>G

Surrounding Variants

1 paper

NM_020922.5

p.D1607E

c.4821C>A

1 paper

NM_020922.5

p.T1604A

c.4810A>G

1 paper

NM_020922.5

p.R1599H

c.4796G>A

3 papers

NM_020922.5

p.R1587H

c.4760G>A

1 paper

NM_020922.5

p.R1565C

c.4693C>T

1 paper

NM_020922.5

p.V1549I

c.4645G>A

1 paper

NM_020922.5

p.K1543Splc

c.4629-1G>C

1 paper

NM_020922.5

p.S1518C

c.4553C>G

1 paper

NM_020922.5

p.E1502K

c.4504G>A

1 paper

NM_020922.5

p.T1442N

c.4325C>A

1 paper

NM_020922.5

p.V1433M

c.4297G>A

1 paper

NM_020922.5

p.K1407R

c.4220A>G