Varaico: Literature-Extracted Genetic Variants

WNK3

144 papers

RefSeq Summary

This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved l...

Pfam Domains

Pkinaseaa 147–405UCSCProtein kinase domain

OSR1_Caa 426–489UCSCOxidative-stress-responsive kinase 1 C-terminal domain

CCTL2_WNKaa 743–819UCSCWNK CCTL2 domain

Gene Aliases

HGNC Name

WNK lysine deficient protein kinase 3

HGNC Previous Symbol

PRKWNK3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_020922.5

p.L1322F

c.3966G>C

Surrounding Variants

1 paper

NM_020922.5

p.L1322F

c.3966G>T

1 paper

NM_020922.5

p.N1323K

c.3969T>G

1 paper

NM_020922.5

p.N1323K

c.3969T>A

1 paper

NM_020922.5

p.S1315S

c.3945C>T

1 paper

NM_020922.5

p.R1293H

c.3878G>A

1 paper

NM_020922.5

p.R1281W

c.3841C>T

1 paper

NM_020922.5

p.A1277P

c.3829G>C

1 paper

NM_020922.5

p.R1271R

c.3813C>A

2 papers

NM_020922.5

p.R1271H

c.3812G>A

1 paper

NM_020922.5

p.R1271C

c.3811C>T

2 papers

NM_020922.5

p.K1266R

c.3797A>G

1 paper

NM_020922.5

p.L1260I

c.3778C>A