Varaico: Literature-Extracted Genetic Variants

WNK3

144 papers

RefSeq Summary

This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved l...

Pfam Domains

Pkinaseaa 147–405UCSCProtein kinase domain

OSR1_Caa 426–489UCSCOxidative-stress-responsive kinase 1 C-terminal domain

CCTL2_WNKaa 743–819UCSCWNK CCTL2 domain

Gene Aliases

HGNC Name

WNK lysine deficient protein kinase 3

HGNC Previous Symbol

PRKWNK3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_020922.5

p.S1198L

c.3593C>T

Surrounding Variants

1 paper

NM_020922.5

p.D1203N

c.3607G>A

1 paper

NM_020922.5

p.N1188K

c.3564T>G

1 paper

NM_020922.5

p.N1188K

c.3564T>A

1 paper

NM_020922.5

p.N1188S

c.3563A>G

2 papers

NM_020922.5

p.H1217Y

c.3649C>T

1 paper

NM_020922.5

p.N1177H

c.3529A>C

1 paper

NM_020922.5

p.H1217_E1218Splc

c.3651+13C>A

1 paper

NM_020922.5

p.I1161_A1162insFs

c.3483_3484dupAG

1 paper

NM_020922.5

p.S1140_S1143del4

c.3418_3428del12

1 paper

NM_020922.5

p.L1120V

c.3358T>G

1 paper

NM_020922.5

p.R1109Q

c.3326G>A

1 paper

NM_020922.5

p.P1101L

c.3302C>T