Varaico: Literature-Extracted Genetic Variants

WNK3

144 papers

RefSeq Summary

This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved l...

Pfam Domains

Pkinaseaa 147–405UCSCProtein kinase domain

OSR1_Caa 426–489UCSCOxidative-stress-responsive kinase 1 C-terminal domain

CCTL2_WNKaa 743–819UCSCWNK CCTL2 domain

Gene Aliases

HGNC Name

WNK lysine deficient protein kinase 3

HGNC Previous Symbol

PRKWNK3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_020922.5

p.R916W

c.2746C>T

Surrounding Variants

3 papers

NM_020922.5

p.E913K

c.2737G>A

1 paper

NM_020922.5

p.R929C

c.2785C>T

1 paper

NM_020922.5

p.R929L

c.2786G>T

1 paper

NM_020922.5

p.G944V

c.2831G>T

1 paper

NM_020922.5

p.K945_E948del4

c.2833_2843del12

1 paper

NM_020922.5

p.E964delFs

c.2892delT

1 paper

NM_020922.5

p.T995I

c.2984C>T

1 paper

NM_020922.5

p.P1041S

c.3121C>T

1 paper

NM_020922.5

p.L890V

c.2668C>G

1 paper

NM_020922.5

p.S886C

c.2657C>G

1 paper

NM_020922.5

p.R882C

c.2644C>T

1 paper

NM_020922.5

p.N881K

c.2643C>G