Varaico: Literature-Extracted Genetic Variants

WNK3

144 papers

RefSeq Summary

This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved l...

Pfam Domains

Pkinaseaa 147–405UCSCProtein kinase domain

OSR1_Caa 426–489UCSCOxidative-stress-responsive kinase 1 C-terminal domain

CCTL2_WNKaa 743–819UCSCWNK CCTL2 domain

Gene Aliases

HGNC Name

WNK lysine deficient protein kinase 3

HGNC Previous Symbol

PRKWNK3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_020922.5

p.A317V

c.950C>T

Surrounding Variants

1 paper

NM_020922.5

p.F315_M316delFs

c.945_948del4

2 papers

NM_020922.5

p.E314A

c.941A>C

2 papers

NM_020922.5

p.E314Q

c.940G>C

1 paper

NM_020922.5

p.D326G

c.977A>G

1 paper

NM_020922.5

p.S328A

c.982T>G

1 paper

NM_020922.5

p.V329I

c.985G>A

2 papers

NM_020922.5

p.S344L

c.1031C>T

2 papers

NM_020922.5

p.Y346F

c.1037A>T

1 paper

NM_020922.5

p.P347A

c.1039C>G

1 paper

NM_020922.5

p.C351*

c.1053T>A

1 paper

NM_020922.5

p.T362delFs

c.1085_1086delAG

1 paper

NM_020922.5

p.S363_G364Splc

c.1089+1G>A