Varaico: Literature-Extracted Genetic Variants

WNK3

144 papers

RefSeq Summary

This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved l...

Pfam Domains

Pkinaseaa 147–405UCSCProtein kinase domain

OSR1_Caa 426–489UCSCOxidative-stress-responsive kinase 1 C-terminal domain

CCTL2_WNKaa 743–819UCSCWNK CCTL2 domain

Gene Aliases

HGNC Name

WNK lysine deficient protein kinase 3

HGNC Previous Symbol

PRKWNK3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_020922.5

p.M230T

c.689T>C

Surrounding Variants

1 paper

NM_020922.5

p.V226_T227delFs

c.678_681del4

2 papers

NM_020922.5

p.E214A

c.641A>C

1 paper

NM_020922.5

p.R208R

c.624A>G

1 paper

NM_020922.5

p.N205S

c.614A>G

1 paper

NM_020922.5

p.P204R

c.611C>G

1 paper

NM_020922.5

p.P204S

c.610C>T

1 paper

NM_020922.5

p.L201H

c.602T>A

1 paper

NM_020922.5

p.Y238F

c.713A>T

1 paper

NM_020922.5

p.K240Q

c.718A>C

1 paper

NM_020922.5

p.K240_R241delFs

c.720_723del4

1 paper

NM_020922.5

p.L250delFs

c.748delA

1 paper

NM_020922.5

p.P269_I271delFs

c.805_812del8