Varaico: Literature-Extracted Genetic Variants

WNK3

144 papers

RefSeq Summary

This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved l...

Pfam Domains

Pkinaseaa 147–405UCSCProtein kinase domain

OSR1_Caa 426–489UCSCOxidative-stress-responsive kinase 1 C-terminal domain

CCTL2_WNKaa 743–819UCSCWNK CCTL2 domain

Gene Aliases

HGNC Name

WNK lysine deficient protein kinase 3

HGNC Previous Symbol

PRKWNK3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_020922.5

p.M1V

c.1A>G

Surrounding Variants

1 paper

NM_020922.5

p.D7N

c.19G>A

1 paper

NM_020922.5

p.P8L

c.23C>T

1 paper

NM_020922.5

p.R25G

c.73A>G

1 paper

NM_020922.5

p.Q28insFs

c.82dupC

1 paper

NM_020922.5

p.V35insFs

c.103dupG

1 paper

NM_020922.5

p.A37A

c.111T>A

1 paper

NM_020922.5

p.L39I

c.115C>A

1 paper

NM_020922.5

p.T45_F46delFs

c.135_136delAG

1 paper

NM_020922.5

p.V71F

c.211G>T

1 paper

NM_020922.5

p.S74L

c.221C>T

1 paper

NM_020922.5

p.K77I

c.230A>T

1 paper

NM_020922.5

p.E79G

c.236A>G