Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

1–12 of 2183 variants

49 papers

NM_024426.6

p.S483Splc

c.1447+4C>T

49 papers

NM_024426.6

p.S483Splc

c.1447+5G>A

37 papers

NM_024426.6

p.R394C

c.1180C>T

32 papers

NM_024426.6

p.Q462*

c.1384C>T

22 papers

NM_024426.6

p.R467W

c.1399C>T

17 papers

NM_024426.6

p.V379fs

c.1135_1136fs

17 papers

NM_024426.6

p.R467Q

c.1400G>A

14 papers

NM_024426.6

p.P381Q

c.1142C>A

13 papers

NM_024426.6

p.Q301*

c.901C>T

12 papers

NM_024426.6

p.D469N

c.1405G>A

10 papers

NM_024426.6

p.M1P

c.2T>C

10 papers

NM_024426.6

p.Q265*

c.793C>T