Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.K481Q

c.1441A>C

Surrounding Variants

1 paper

NM_024426.6

p.K481*

c.1441A>T

1 paper

NM_024426.6

p.K481E

c.1441A>G

1 paper

NM_024426.6

p.G480G

c.1440T>G

1 paper

NM_024426.6

p.G480G

c.1440T>C

1 paper

NM_024426.6

p.G480G

c.1440T>A

1 paper

NM_024426.6

p.K481I

c.1442A>T

1 paper

NM_024426.6

p.K481T

c.1442A>C

2 papers

NM_024426.6

p.G480V

c.1439G>T

1 paper

NM_024426.6

p.G480A

c.1439G>C

1 paper

NM_024426.6

p.G480D

c.1439G>A

1 paper

NM_024426.6

p.K481N

c.1443A>T

1 paper

NM_024426.6

p.K481K

c.1443A>G