Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.T479I

c.1436C>T

Surrounding Variants

1 paper

NM_024426.6

p.T479R

c.1436C>G

1 paper

NM_024426.6

p.T479K

c.1436C>A

1 paper

NM_024426.6

p.T479T

c.1437A>T

1 paper

NM_024426.6

p.T479S

c.1435A>T

5 papers

NM_024426.6

p.T479T

c.1437A>G

2 papers

NM_024426.6

p.T479A

c.1435A>G

1 paper

NM_024426.6

p.T479T

c.1437A>C

1 paper

NM_024426.6

p.T479P

c.1435A>C

1 paper

NM_024426.6

p.H478_T479insFs

c.1434_1435insA

2 papers

NM_024426.6

p.H478Q

c.1434T>G

1 paper

NM_024426.6

p.H478H

c.1434T>C

2 papers

NM_024426.6

p.H478Q

c.1434T>A