Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.H474P

c.1421A>C

Surrounding Variants

1 paper

NM_024426.6

p.H474L

c.1421A>T

4 papers

NM_024426.6

p.H474R

c.1421A>G

7 papers

NM_024426.6

p.H474Y

c.1420C>T

NM_000378.6

p.H457Y

c.1369C>T

1 paper

NM_024426.6

p.H474H

c.1422C>T

2 papers

NM_024426.6

p.H474Q

c.1422C>G

1 paper

NM_024426.6

p.H474D

c.1420C>G

2 papers

NM_024426.6

p.H474Q

c.1422C>A

1 paper

NM_024426.6

p.H474N

c.1420C>A

1 paper

NM_024426.6

p.T473T

c.1419C>G

1 paper

NM_024426.6

p.T473T

c.1419C>A

1 paper

NM_024426.6

p.T475fs

c.1423_1424fs

1 paper

NM_024426.6

p.T475S

c.1423A>T