Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.K472R

c.1415A>G

Surrounding Variants

1 paper

NM_024426.6

p.K472M

c.1415A>T

1 paper

NM_024426.6

p.K472T

c.1415A>C

1 paper

NM_024426.6

p.K472N

c.1416G>T

1 paper

NM_024426.6

p.K472_T473insFs

c.1416_1417insC

1 paper

NM_024426.6

p.K472N

c.1416G>C

1 paper

NM_024426.6

p.K472K

c.1416G>A

1 paper

NM_024426.6

p.K472*

c.1414A>T

1 paper

NM_024426.6

p.K472E

c.1414A>G

1 paper

NM_024426.6

p.K472Q

c.1414A>C

1 paper

NM_024426.6

p.K472_T473insG

c.1414_1418ins3

1 paper

NM_024426.6

p.L471L

c.1413G>T

1 paper

NM_024426.6

p.L471L

c.1413G>C