Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_024426.6

p.D469V

c.1406A>T

Surrounding Variants

4 papers

NM_024426.6

p.D469G

c.1406A>G

2 papers

NM_024426.6

p.D469A

c.1406A>C

3 papers

NM_024426.6

p.D469Y

c.1405G>T

3 papers

NM_024426.6

p.D469H

c.1405G>C

13 papers

NM_024426.6

p.D469N

c.1405G>A

NM_001198551.2

p.D252N

c.754G>A

1 paper

NM_024426.6

p.D469D

c.1407C>T

2 papers

NM_024426.6

p.D469E

c.1407C>A

5 papers

NM_024426.6

p.H470Y

c.1408C>T

2 papers

NM_000378.6

p.S451S

c.1353C>T

NM_024426.6

p.S468S

c.1404C>T

1 paper

NM_024426.6

p.H470D

c.1408C>G

1 paper

NM_024426.6

p.S468S

c.1404C>G

1 paper

NM_024426.6

p.H470N

c.1408C>A