Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.S468S

c.1404C>G

Surrounding Variants

2 papers

NM_000378.6

p.S451S

c.1353C>T

NM_024426.6

p.S468S

c.1404C>T

1 paper

NM_024426.6

p.S468S

c.1404C>A

3 papers

NM_024426.6

p.D469Y

c.1405G>T

3 papers

NM_024426.6

p.D469H

c.1405G>C

13 papers

NM_024426.6

p.D469N

c.1405G>A

NM_001198551.2

p.D252N

c.754G>A

2 papers

NM_024426.6

p.S468F

c.1403C>T

1 paper

NM_024426.6

p.S468C

c.1403C>G

1 paper

NM_024426.6

p.S468Y

c.1403C>A

1 paper

NM_024426.6

p.S468A

c.1402T>G

3 papers

NM_024426.6

p.S468P

c.1402T>C

NM_000378.6

p.S451P

c.1351T>C

1 paper

NM_024426.6

p.S468T

c.1402T>A

1 paper

NM_024426.6

p.S468fs

c.1402_1403fs