Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.R467R

c.1399C>A

Surrounding Variants

24 papers

NM_024426.6

p.R467W

c.1399C>T

NM_001198551.2

p.R250W

c.748C>T

5 papers

NM_024426.6

p.R467G

c.1399C>G

1 paper

NM_024426.6

p.R467_S468insT

c.1399_1403ins3

1 paper

NM_024426.6

p.R467_S468ins8

c.1399_1403ins24

4 papers

NM_024426.6

p.R467L

c.1400G>T

1 paper

NM_024426.6

p.R467insFs

c.1400_1401ins4

5 papers

NM_024426.6

p.R467P

c.1400G>C

17 papers

NM_024426.6

p.R467Q

c.1400G>A

1 paper

NM_024426.6

p.S466S

c.1398C>T

1 paper

NM_024426.6

p.S466S

c.1398C>G

1 paper

NM_024426.6

p.S466S

c.1398C>A

1 paper

NM_024426.6

p.R467R

c.1401G>T