Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_024426.6

p.S466F

c.1397C>T

Surrounding Variants

1 paper

NM_024426.6

p.S466C

c.1397C>G

1 paper

NM_024426.6

p.S466Y

c.1397C>A

1 paper

NM_024426.6

p.S466A

c.1396T>G

1 paper

NM_024426.6

p.S466P

c.1396T>C

1 paper

NM_024426.6

p.S466T

c.1396T>A

1 paper

NM_024426.6

p.S466S

c.1398C>T

1 paper

NM_024426.6

p.S466S

c.1398C>G

1 paper

NM_024426.6

p.S466S

c.1398C>A

24 papers

NM_024426.6

p.R467W

c.1399C>T

NM_001198551.2

p.R250W

c.748C>T

1 paper

NM_024426.6

p.F465F

c.1395C>T

5 papers

NM_024426.6

p.R467G

c.1399C>G

4 papers

NM_024426.6

p.F465L

c.1395C>G