Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.K464fs

c.1390_1391fs

Surrounding Variants

1 paper

NM_024426.6

p.K464*

c.1390A>T

1 paper

NM_024426.6

p.K464E

c.1390A>G

2 papers

NM_024426.6

p.K464Q

c.1390A>C

1 paper

NM_024426.6

p.R463delFs

c.1388_1389delTC

1 paper

NM_024426.6

p.F456_R463del8

c.1366_1388del24

1 paper

NM_024426.6

p.K464M

c.1391A>T

1 paper

NM_024426.6

p.R463R

c.1389A>T

3 papers

NM_024426.6

p.K464R

c.1391A>G

1 paper

NM_024426.6

p.R463R

c.1389A>G

1 paper

NM_024426.6

p.K464T

c.1391A>C

1 paper

NM_024426.6

p.R463R

c.1389A>C

1 paper

NM_024426.6

p.R463_K464insFs

c.1389_1390ins4