Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.R463R

c.1387C>A

Surrounding Variants

10 papers

NM_024426.6

p.R463*

c.1387C>T

NM_001198551.2

p.R246*

c.736C>T

1 paper

NM_024426.6

p.R463G

c.1387C>G

1 paper

NM_024426.6

p.Q462delFs

c.1386delC

1 paper

NM_024426.6

p.R463L

c.1388G>T

1 paper

NM_024426.6

p.Q462H

c.1386G>T

2 papers

NM_024426.6

p.R463P

c.1388G>C

1 paper

NM_024426.6

p.Q462H

c.1386G>C

3 papers

NM_024426.6

p.R463Q

c.1388G>A

1 paper

NM_024426.6

p.Q462Q

c.1386G>A

1 paper

NM_024426.6

p.P455_Q462del8

c.1363_1385del24

1 paper

NM_024426.6

p.K454_Q462delFs

c.1360_1385del26

2 papers

NM_000378.6

p.Q445L

c.1334A>T

NM_024426.6

p.Q462L

c.1385A>T