Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000378.6

p.Q445L

c.1334A>T

NM_024426.6

p.Q462L

c.1385A>T

Surrounding Variants

1 paper

NM_024426.6

p.Q462R

c.1385A>G

1 paper

NM_024426.6

p.Q462P

c.1385A>C

1 paper

NM_024426.6

p.Q462delFs

c.1384delG

1 paper

NM_024426.6

p.Q462H

c.1386G>T

1 paper

NM_024426.6

p.Q462H

c.1386G>C

1 paper

NM_024426.6

p.Q462Q

c.1386G>A

1 paper

NM_024426.6

p.K454_Q462delFs

c.1360_1385del26

33 papers

NM_024426.6

p.Q462*

c.1384C>T

NM_000378.6

p.Q445*

c.1333C>T

2 papers

NM_024426.6

p.Q462E

c.1384C>G

1 paper

NM_024426.6

p.Q462K

c.1384C>A

1 paper

NM_024426.6

p.F456_C461del6

c.1366_1382del18

1 paper

NM_024426.6

p.C461_Q462insFs

c.1383_1384ins7