Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_024426.6

p.C461R

c.1381T>C

Surrounding Variants

1 paper

NM_024426.6

p.C461G

c.1381T>G

1 paper

NM_024426.6

p.C461S

c.1381T>A

1 paper

NM_024426.6

p.T460T

c.1380T>G

1 paper

NM_024426.6

p.T460T

c.1380T>C

1 paper

NM_024426.6

p.T460T

c.1380T>A

1 paper

NM_024426.6

p.C461F

c.1382G>T

1 paper

NM_024426.6

p.C461S

c.1382G>C

2 papers

NM_024426.6

p.C461Y

c.1382G>A

1 paper

NM_024426.6

p.C461_Q462insFs

c.1383_1384ins7

1 paper

NM_024426.6

p.C461W

c.1383T>G

1 paper

NM_024426.6

p.C461C

c.1383T>C

1 paper

NM_024426.6

p.C461*

c.1383T>A