Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.Q457L

c.1370A>T

Surrounding Variants

1 paper

NM_024426.6

p.Q457R

c.1370A>G

1 paper

NM_024426.6

p.Q457P

c.1370A>C

1 paper

NM_024426.6

p.Q457H

c.1371G>T

2 papers

NM_024426.6

p.Q457fs

c.1369_1370fs

1 paper

NM_024426.6

p.Q457H

c.1371G>C

2 papers

NM_024426.6

p.Q457Q

c.1371G>A

5 papers

NM_024426.6

p.Q457*

c.1369C>T

NM_000378.6

p.Q440*

c.1318C>T

1 paper

NM_024426.6

p.Q457E

c.1369C>G

6 papers

NM_024426.6

p.Q457_C458ins4

c.1369_1373ins12

1 paper

NM_024426.6

p.Q457K

c.1369C>A

1 paper

NM_024426.6

p.V453_F456delFs

c.1358_1368del11

1 paper

NM_024426.6

p.C458G

c.1372T>G