Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_024426.6

p.F456L

c.1368C>A

Surrounding Variants

2 papers

NM_024426.6

p.F456F

c.1368C>T

3 papers

NM_024426.6

p.F456L

c.1368C>G

1 paper

NM_024426.6

p.F456C

c.1367T>G

1 paper

NM_024426.6

p.F456S

c.1367T>C

1 paper

NM_024426.6

p.F456Y

c.1367T>A

5 papers

NM_024426.6

p.Q457*

c.1369C>T

NM_000378.6

p.Q440*

c.1318C>T

1 paper

NM_024426.6

p.Q457E

c.1369C>G

6 papers

NM_024426.6

p.Q457_C458ins4

c.1369_1373ins12

1 paper

NM_024426.6

p.Q457K

c.1369C>A

1 paper

NM_024426.6

p.V453_F456delFs

c.1358_1368del11

1 paper

NM_024426.6

p.F456_Q457ins5

c.1366_1370ins15

1 paper

NM_024426.6

p.F456_Q457ins8

c.1366_1370ins24