Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.P455Q

c.1364C>A

Surrounding Variants

2 papers

NM_024426.6

p.P455L

c.1364C>T

1 paper

NM_024426.6

p.P455R

c.1364C>G

3 papers

NM_024426.6

p.P455S

c.1363C>T

1 paper

NM_024426.6

p.P455A

c.1363C>G

1 paper

NM_024426.6

p.P455_F456ins5

c.1363_1367ins15

2 papers

NM_024426.6

p.P455_F456ins8

c.1363_1367ins24

2 papers

NM_024426.6

p.P455_F456ins10

c.1363_1367ins30

1 paper

NM_024426.6

p.P455T

c.1363C>A

1 paper

NM_024426.6

p.P455P

c.1365A>T

1 paper

NM_024426.6

p.P455P

c.1365A>G

1 paper

NM_024426.6

p.P455P

c.1365A>C

1 paper

NM_024426.6

p.F456_Q457ins5

c.1366_1370ins15