Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.V453_K454insFs

c.1359_1360insGT

Surrounding Variants

3 papers

NM_024426.6

p.K454*

c.1360A>T

1 paper

NM_024426.6

p.K454E

c.1360A>G

1 paper

NM_024426.6

p.V453delFs

c.1358_1359delCA

1 paper

NM_024426.6

p.V453V

c.1359G>T

1 paper

NM_024426.6

p.V453V

c.1359G>C

1 paper

NM_024426.6

p.V453V

c.1359G>A

1 paper

NM_024426.6

p.V453delFs

c.1358delA

1 paper

NM_024426.6

p.K454I

c.1361A>T

1 paper

NM_024426.6

p.K454R

c.1361A>G

1 paper

NM_024426.6

p.K454T

c.1361A>C

1 paper

NM_024426.6

p.V453_K454delins

c.1357_1361delinsAGTAG

1 paper

NM_024426.6

p.V453G

c.1358T>G