Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000378.6

p.S400G

c.1198A>G

Surrounding Variants

2 papers

NM_024426.6

p.S417I

c.1250G>T

1 paper

NM_024426.6

p.H416R

c.1247A>G

1 paper

NM_024426.6

p.H416_S417insCC

c.1246_1250ins6

1 paper

NM_024426.6

p.M415fs

c.1243_1244fs

1 paper

NM_024426.6

p.R418delFs

c.1252delT

2 papers

NM_024426.6

p.M415K

c.1244T>A

2 papers

NM_024426.6

p.K419E

c.1255A>G

1 paper

NM_024426.6

p.K419ins2

c.1255_1256ins6

1 paper

NM_024426.6

p.K419_H420ins4

c.1255_1259ins12

1 paper

NM_024426.6

p.K419_H420ins8

c.1255_1259ins24

1 paper

NM_024426.6

p.Q414delFs

c.1242delC

1 paper

NM_024426.6

p.Q414fs

c.1240_1241fs