Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.R406K

c.1217G>A

Surrounding Variants

1 paper

NM_024426.6

p.R406insFs

c.1217_1218dupGA

2 papers

NM_024426.6

p.K405fs

c.1213_1214fs

1 paper

NM_024426.6

p.K405_R406insFs

c.1215_1216insA

1 paper

NM_024426.6

p.K405_R406insFs

c.1215_1216ins5

2 papers

NM_024426.6

p.K405delFs

c.1213_1214delTT

1 paper

NM_001198551.2

p.K188M

c.563A>T

3 papers

NM_024426.6

p.K405R

c.1214A>G

1 paper

NM_024426.6

p.Y407C

c.1220A>G

3 papers

NM_024426.6

p.Y407_F408insFs

c.1221_1222insC

1 paper

NM_024426.6

p.N404Fs

c.1212delinsACTFs

1 paper

NM_024426.6

p.F408V

c.1222T>G

1 paper

NM_024426.6

p.F408L

c.1222T>C