Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.F396_M397insFs

c.1188_1189ins17

Surrounding Variants

1 paper

NM_000378.6

p.M380Fs

c.1138delinsGTFs

1 paper

NM_000378.6

p.M380insFs

c.1138_1139ins8

1 paper

NM_024426.6

p.C398R

c.1192T>C

1 paper

NM_000378.6

p.C381S

c.1141T>A

1 paper

NM_000378.6

p.M380delFs

c.1140delC

1 paper

NM_024426.6

p.P395H

c.1184C>A

1 paper

NM_024426.6

p.C398W

c.1194T>G

1 paper

NM_000378.6

p.R377_P378insFs

c.1131_1132insT

1 paper

NM_024426.6

p.R394fs

c.1180_1181fs

4 papers

NM_024426.6

p.R394L

c.1181G>T

1 paper

NM_000378.6

p.A382insFs

c.1144_1145ins4

1 paper

NM_024426.6

p.E392_R394ins1

c.1175_1180dup6