Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

37 papers

NM_024426.6

p.R394C

c.1180C>T

Surrounding Variants

7 papers

NM_024426.6

p.R394G

c.1180C>G

1 paper

NM_024426.6

p.R394insFs

c.1180_1181insA

1 paper

NM_024426.6

p.R394S

c.1180C>A

4 papers

NM_024426.6

p.R394L

c.1181G>T

1 paper

NM_024426.6

p.E392_R394ins1

c.1175_1180dup6

6 papers

NM_024426.6

p.R394P

c.1181G>C

6 papers

NM_024426.6

p.R394H

c.1181G>A

1 paper

NM_024426.6

p.K393_R394del1

c.1178_1180delGTT

1 paper

NM_024426.6

p.K393fs

c.1177_1178fs

1 paper

NM_000378.6

p.R377_P378insFs

c.1131_1132insT

1 paper

NM_024426.6

p.R394fs

c.1180_1181fs

1 paper

NM_024426.6

p.E392delFs

c.1176delC