Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.S391_E392insFs

c.1173_1174ins4

Surrounding Variants

1 paper

NM_024426.6

p.S391_E392insFs

c.1173_1174insA

1 paper

NM_024426.6

p.S391_E392insFs

c.1173_1174ins11

1 paper

NM_024426.6

p.S391insFs

c.1172_1173insC

1 paper

NM_024426.6

p.E392fs

c.1174_1175fs

1 paper

NM_000378.6

p.S374G

c.1120A>G

1 paper

NM_024426.6

p.T390fs

c.1168_1169fs

1 paper

NM_024426.6

p.V379_T390Fs

c.1136_1170delinsGAGFs

2 papers

NM_024426.6

p.T390S

c.1169C>G

1 paper

NM_024426.6

p.T390insFs

c.1169_1170insT

1 paper

NM_001198551.2

p.E172_T173del1

c.515_517delTCT

1 paper

NM_024426.6

p.E392delFs

c.1176delC

1 paper

NM_024426.6

p.T390P

c.1168A>C